Fungistatic effect of hydroxychloroquine, lessons from a case

Chloroquine/Hydroxychloroquine AND SARS-CoV 2; lessons from case-control studies

Chloroquine has several disadvantages consisting hypoglycemia, diarrhea, prolong QTc interval, and AV block (21-22). In addition, Gendelman et al., recently published an article about inefficacy of continuous Hydroxychloroquine or colchicine therapy for prevention of SARS-CoV 2 infection (23). According to recent RCTs, HCQ has no therapeutic effects on prevention or improvment of major outcomes...

Hydroxychloroquine Induced Retinopathy: A Case Series

Background and Purpose: Occular toxicity is one of the most important complications of Hydroxychloroquine. Not any type of treatment has so far been found and recommended for this disorder. The purpose of this study was to report some characteristics of patients with Hydroxychloroquine Induced Retinopathy.    Materials and Methods: From 107 patients with rheumatoid arthritis (...

The Effect of Hydroxychloroquine on Symptoms of Knee Osteoarthritis: A Double-Blind Randomized Controlled Clinical Trial

Background: Osteoarthritis is a degenerative joint disorder of articular cartilage and is the most common type of arthritis in the elderly. There are only a few reports regarding the use of Hydroxychloroquine in the treatment of osteoarthritis. Methods: To investigate the effects of Hydroxychloroquine on the symptoms of mild to moderate knee osteoarthritis (Kellgren and Lawrence grade II and II...

Practical Lessons from the Small Bowel Bleeding Lesions: A Case Report on Small Bowel Cavernous Hemangioma

Hydroxychloroquine-induced Unusual Generalized Pustular Cutaneous Reaction As a New Clinical Entity: A Case Series

Background: Pustular Psoriasis (PP) and Acute Generalized Exanthematous Pustulosis (AGEP) clinically resemble each other. There are many patients with generalized pustular presentations like hydroxychloroquine-induced pustular reaction who do not completely fall within PP or AGEP categories and needed to be more evaluated. So we examined a large series of these reactions to hyd...